早期使用重组人脑利钠肽对急性心肌梗死并心力衰竭患者心功能的影响及安全性观察

摘要/Abstract

摘要： 目的急性心肌梗死合并心力衰竭患者早期使用重组人脑利钠肽对其心功能的影响及安全性观察。方法回顾性选取60例患者,这些患者在2023年5月至2024年5月期间,在我院心血管内科被诊断为急性心肌梗死并合并心力衰竭。将这些患者分为两组,即对照组（常规抗心力衰竭治疗,n=30）和观察组（常规抗心力衰竭治疗联合重组人脑利钠肽,n=30）。比较了两组患者采用不同治疗方案后的有效率、心功能变化及不良反应情况,以便进一步分析比较。结果治疗后观察组患者的氨基末端B型脑钠肽前体水平、左心室射血分数、左心室收缩末期内径以及左心室舒张末期内径相比对照组改善更明显（P<0.05）;观察组的治疗总有效率为90%,明显高于对照组的70%;观察组的不良反应发生率为6.66%,明显低于对照组的23.33%。结论在急性心肌梗死和心力衰竭的早期阶段,使用重组人脑利钠肽能够显著提升病人的心脏功能,并且其安全性较高

关键词: 急性心肌梗死, 心力衰竭, 重组人脑利钠肽, 安全性

肖华丽, 陈海刚, 崔海东, 曾洁, 万林林, 杨苗苗, 茶春喜. 早期使用重组人脑利钠肽对急性心肌梗死并心力衰竭患者心功能的影响及安全性观察[J]. 心血管病防治知识, 2024, 14(19): 3-6.

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