脉压水平与空腹血糖受损的关联性研究

摘要/Abstract

摘要： 目的探讨中国健康成年人群中脉压与空腹血糖受损（IFG）的相关性。方法选取中国人群队列研究中且符合纳入排除标准的健康人群为研究对象,计算脉压并根据脉压四分位数将其分为四组,采用多因素Logistic回归分析模型估计不同脉压组的IFG患病风险及95%置信区间,并进行分层分析和敏感性分析。结果纳入的209,635例研究对象中有6 904例患有IFG,随脉压水平的增加,IFG的患病率逐渐增加（P<0.001）。多因素Logistic回归分析结果显示,校正多种混杂因素后,脉压每增加10 mmHg,IFG患病风险增加16%（OR=1.16, 95%CI： 1.13-1.18）。与Q1组相比,Q3组患病风险增加26%（OR=1.26, 95%CI：1.16-1.36）,Q4组增加48%（OR=1.48, 95%CI：1.37-1.59）。此外,不同年龄、不同性别和不同BMI的人群中这种趋势一致。排除高血压人群,脉压与IFG的关联依旧稳健。结论脉压与IFG患病率呈正向关联,高脉压是IFG的危险因素之一。

田田, 拜媛. 脉压水平与空腹血糖受损的关联性研究[J]. 心血管病防治知识, 2024, 14(10): 10-13.

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