Objective To investigate the influenceof hyperuricemia on the severity of coronary stenosis anddisease conditions of patients with acute myocardial infarction (AMI)and their prognosis after percutaneous coronary intervention (PCI). Methods A retrospective analysis was performed for thedata of 298 patients who underwent coronary angiography in Department of Cardiovascular Medicine inour hospital from May 2021 to October 2022, and they were divided into three groups according to related examination results. Clinical data were compared betweenthe three groups, and the correlationbetween the level of serum uric acid(SUA)and the degree of coronary artery disease was analyzed. The AMI group was divided into two subgroups based on the diagnosis of hyperuricemia, and the influence of hyperuricemia on the degree of coronary stenosis, diseaseseverity, and prognosis wasanalyzed. Alogistic regression analysis was used to investigatethe risk factors formajor adverse cardiacevents (MACE) in and out of hospital inAMI patients. Results The patients withAMIhad a significantly higher level of SUA than those with unstable angina pectoris (UA) or stable angina pectoris (SAP)(P<0.05). SUA level was positively correlated with Gensini score for coronary stenosis in all patients(r = 0.171, P<0.05), and the patients withAMI had a significantly higher Gensini score than the other two groups (P<0.05). TheAMI patients diagnosed with hyperuricemia had significantly higher Gensini score, Grace score, and proportion of high-risk patients than those without hyperuricemia (P<0.05), with a significantly higher possibility of MACE in and out of hospital (P<0.05). The logistic regression analysis showed that hyperuricemia was an independent risk factor for MACE in and out of hospital in patients with AMI (P<0.05). Conclusion Hyperuricemia can increasethe severity of coronary stenosis and disease conditions and lead to a poorer prognosis of AMI patients.

Objective To investigate the rehabilitation effect of walking training in patients with lower limb arteriosclerosis obliterans(ASO). Methods A total of 59 patients with Fontaine stage II-III ASO who underwent surgical treatment in Department of Vascular Surgery in our hospital from July 2020 to July 2022 were enrolled and randomly divided into control group with 30 patients (without regular walking training) and experimental group with 29 patients (regular progressive walking training), andthe two groups were compared in terms of the improvement inclaudication distance, ankle-brachial index (ABI),body mass index(BMI), and blood lipids after 6 months. Results There was no significant difference in the composition ratio of patients with different Fontaine stages between the two groups (P>0.05). Compared with the control group, the experimental group had significant improvements in claudication distance, ABI, and BMI after 6 months of training (P<0.05), and there was no significant difference in blood lipids between the experimental group and the control group due to the difference in blood lipid examination and the administration of lipid-lowering drugs (P>0.05). Conclusion Walking training can significantly improve BMI, ABI of bilateral limbs, and claudication distance in patients with Fontaine stage II-IIIASO, which provides a practical, simple, and economicalrehabilitation method for ASO patients.