噻嗪类利尿剂在高血压治疗中的研究进展

摘要/Abstract

摘要： 为了进一步使高血压患者得到最佳地血压控制,让噻嗪类利尿剂发挥应有的重要作用,经搜索和收集新近发表的关于噻嗪类利尿剂治疗高血压的最新研究结果,进行总结、分析和归纳。研究显示单一使用噻嗪类利尿剂治疗高血压,对减少总的心血管病事件的效果不亚于其它种类降压药（肾素-血管紧张素-醛固酮抑制剂、钙拮抗剂及β受体阻滞剂）,并且噻嗪类利尿剂与肾素-血管紧张素-醛固酮抑制剂联合使用效果更好、更安全;2021年世界卫生组织（WHO）发布的《WHO成人高血压药物治疗指南》推荐了噻嗪类利尿剂为一线降压药,综合近期降压药领域的最新研究进展,笔者肯定噻嗪类利尿剂用于治疗高血压的临床效果,安全性好,成本/效益比低,是值得信赖和广泛推广应用的一线降压药。

关键词: 高血压病, 噻嗪类利尿剂, 降压药, 经济学效益

陈春晖, 曾广民, 傅宴, 董广卫, 张娟. 噻嗪类利尿剂在高血压治疗中的研究进展[J]. 心血管病防治知识, 2023, 13(25): 86-90.

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