Objective To investigate the clinical effect of 8-shaped elastic bandage versus spinning hemostat in patients with coronary heart disease (CHD) after percutaneous coronary intervention (PCI) via radial artery puncture, and to provide a reference for subsequent treatment. Methods A total of 300 CHD patients who underwent PCI via radial artery puncture in The Third People’s Hospital of Nanning from July 2022 to July 2023 were enrolled as subjects, and they were divided into control group and experimental group using a random number table, with 150 patients in each group. The patients in the control group used a spinning hemostat after surgery, while those in the experimental group were given an 8-shaped elastic bandage for hemostasis. The two groups were compared in terms of the effect of hemostasis, postoperative wrist circumference, postoperative collateral oxygen supply, postoperative pain assessment based on numerical rating scale (NRS), adverse reactions, and radial artery stenosis/occlusion. Results Compared with the control group, the experimental group had a significant increase in blood oxygen saturation (95.31%±5.96% vs 97.38%±6.63%, t=2.832, P=0.005). Compared with the control group, the experimental group had a significantly lower proportion of patients with postoperative oozing bleeding (14.00% vs 6.00%), wound hematoma (12.67% vs 5.33%), or bandaging again (17.33% vs 7.33%) and a significantly smaller postoperative wrist circumference (18.00±3.42 cm vs 16.02±3.36 cm), with a P value of <0.05 or <0.01. Compared with the control group, the experimental group had a significantly higher proportion of patients with no pain (68.00% vs 88.67%) and a significantly lower proportion of patients with mild pain (15.33% vs 6.67%), moderate pain (14.67% vs 4.67%), limb numbness (9.33% vs 3.33%), limb swelling (10.67% vs 3.33%), limitation of motion (14.00% vs 6.00%), or radial artery stenosis/occlusion (6.00% vs 1.33%), with a P value of <0.05 or <0.01. Conclusion Compared with the spinning hemostat, the 8-shaped elastic bandage can better improve the effect of hemostasis, adverse reactions, and radial artery stenosis/occlusion and is more acceptable to patients; therefore, it holds promise for clinical application.