Abstract: Objective To investigate the value of blood urea nitrogen-to-serum albumin ratio (BAR) in predicting the prognosis of patients with critical chronic heart failure (CHF). Methods A retrospective analysis was performed for 58 patients with critical CHF who were admitted to our hospital from May 2022 to May 2023, and the association between BAR and prognosis was analyzed. Results The prognosis of critical CHF patients had a relatively low degree of association with sex, pH, PCO₂, heart rate, and medical history (chronic obstructive pulmonary disease, hypertension, diabetes, peripheral arterial disease, stroke, and thromboembolism) (all P>0.05), while it had a relatively high degree of association with the factors such as age, body mass index, PO₂, SO₂, systolic blood pressure, diastolic blood pressure, medical history (atrial fibrillation, coronary heart disease, renal insufficiency, myocardial infarction, and sepsis), red blood cell count, white blood cell count, red blood cell distribution width, the proportion of neutrophils, lymphocytes, hemoglobin, lactate dehydrogenase, serum creatinine, blood urea nitrogen, lactic acid, aspartate aminotransferase, alanine aminotransferase, BAR, activated partial thromboplastin time, prothrombin time, and international normalized ratio (INR) (all P<0.05). The multivariate analysis showed that age, diastolic blood pressure, coronary heart disease, sepsis, red blood cell distribution width, serum creatinine, lactic acid, and INR are the factors associated with BAR and death due to CHF. Conclusion BAR can be used as an independent prognostic factor in patients with critical CHF.

Key words: Blood urea nitrogen, Serum albumin, Ratio, Critical chronic heart failure, Prognosis